Cyclohexylamine → HCID 15549758, compound

HRID 2268814Notes

Reaction equation

HRID 2268814 reaction equation
Cl[C:2]1[N:7]2[N:8]=[CH:9][C:10]([C:11]#[N:12])=[C:6]2[N:5]=[C:4]([C:13]([O:15][CH2:16][CH3:17])=[O:14])[C:3]=1[CH2:18][CH2:19]Cl.[CH:21]1([NH2:27])[CH2:26][CH2:25][CH2:24][CH2:23][CH2:22]1>>[C:11]([C:10]1[CH:9]=[N:8][N:7]2[C:2]3[N:27]([CH:21]4[CH2:26][CH2:25][CH2:24][CH2:23][CH2:22]4)[CH2:19][CH2:18][C:3]=3[C:4]([C:13]([O:15][CH2:16][CH3:17])=[O:14])=[N:5][C:6]=12)#[N:12]

Participants

3

Reactant 2

HCID 7965CyclohexylamineHCID 18332853HCID 18332853, compound

Product 1

HCID 15549758HCID 15549758, compoundYield 96.5%

Procedure

The intended compound was obtained in 96.5% yield in the same manner as in Synthesis Example (5) using ethyl 7-chloro-6-(2-chloroethyl)-3-cyanopyrazolo[1,5-a]-pyrimidine-5-carboxylate and cyclohexylamine.

Workup

  1. customThe intended compound was obtained in 96.5% yield in the same manner as in Synthesis Example (5)

Sources & evidence

ORD record
ord-7ea3a1e6756f49599ff760bb200eeed0
Source dataset
uspto-grants-2001_12
Patent number
US06329382B1

Reaction notes

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