Sec-Butylamine → HCID 15549759, compound

HRID 2268815Notes

Reaction equation

HRID 2268815 reaction equation
Cl[C:2]1[N:7]2[N:8]=[CH:9][C:10]([C:11]#[N:12])=[C:6]2[N:5]=[C:4]([C:13]([O:15][CH2:16][CH3:17])=[O:14])[C:3]=1[CH2:18][CH2:19]Cl.[CH:21]([NH2:25])([CH2:23][CH3:24])[CH3:22]>>[CH:21]([N:25]1[C:2]2[N:7]3[N:8]=[CH:9][C:10]([C:11]#[N:12])=[C:6]3[N:5]=[C:4]([C:13]([O:15][CH2:16][CH3:17])=[O:14])[C:3]=2[CH2:18][CH2:19]1)([CH2:23][CH3:24])[CH3:22]

Participants

3

Reactant 2

HCID 24874Sec-ButylamineHCID 18332853HCID 18332853, compound

Product 1

HCID 15549759HCID 15549759, compoundYield 95.6%

Procedure

The intended compound was obtained in 95.6% yield in the same manner as in Synthesis Example (5) using ethyl 7-chloro-6-(2-chloroethyl)-3-cyanopyrazolo[1,5-a]pyrimidine-5-carboxylate and sec-butylamine.

Workup

  1. customThe intended compound was obtained in 95.6% yield in the same manner as in Synthesis Example (5)

Sources & evidence

ORD record
ord-cad08f1384a648c08806fdfa7d9cff18
Source dataset
uspto-grants-2001_12
Patent number
US06329382B1

Reaction notes

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