HRID2268976

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID66589

1-Isocyanatonaphthalene

C11H7NO

结构：CC(Nc1nccc(-n2cnc3cc(-c4ccncc4)ccc32)n1)C1CCCNC1

HCID18332620

未命名化合物

PRODUCTS

生成物

结构：CC(Nc1nccc(-n2cnc3cc(-c4ccncc4)ccc32)n1)C1CCCN(C(=O)Nc2cccc3ccccc23)C1

HCID18332625

未命名化合物

PROCEDURE

实验过程

The title compound was prepared from 2-[1-(piperidin-3-yl)-ethylamino]-4-[5-(pyridin-4-yl)-benzimidazol-1-yl]pyrimidine according to the procedure described in EXAMPLE 29 using 1-naphthylisocyanate. Mass spectrum (ESI) 569.5 (M+1).

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-632076db3aee468aadc3d56511f8e3fc
来源数据集: uspto-grants-2001_12
DOI: 10.6084/m9.figshare.5104873.v1
专利: US06329380B1
来源说明: uspto-grants-2001_12

反应 SMILES

[NH:1]1[CH2:6][CH2:5][CH2:4][CH:3]([CH:7]([NH:9][C:10]2[N:15]=[C:14]([N:16]3[C:20]4[CH:21]=[CH:22][C:23]([C:25]5[CH:30]=[CH:29][N:28]=[CH:27][CH:26]=5)=[CH:24][C:19]=4[N:18]=[CH:17]3)[CH:13]=[CH:12][N:11]=2)[CH3:8])[CH2:2]1.[C:31]1([N:41]=[C:42]=[O:43])[C:40]2[C:35](=[CH:36][CH:37]=[CH:38][CH:39]=2)[CH:34]=[CH:33][CH:32]=1>>[C:31]1([NH:41][C:42]([N:1]2[CH2:6][CH2:5][CH2:4][CH:3]([CH:7]([NH:9][C:10]3[N:15]=[C:14]([N:16]4[C:20]5[CH:21]=[CH:22][C:23]([C:25]6[CH:30]=[CH:29][N:28]=[CH:27][CH:26]=6)=[CH:24][C:19]=5[N:18]=[CH:17]4)[CH:13]=[CH:12][N:11]=3)[CH3:8])[CH2:2]2)=[O:43])[C:40]2[C:35](=[CH:36][CH:37]=[CH:38][CH:39]=2)[CH:34]=[CH:33][CH:32]=1