(R)-5-Bromo-3-(1-methyl-2-pyrrolidinyl methyl)-1H-indole → 5-Bromo-N,N-Dimethyltryptamine

HRID 2268977Notes

Reaction equation

HRID 2268977 reaction equation
[Br:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][CH:6]=[C:5]2[CH2:11][C@H:12]1CC[CH2:14][N:13]1[CH3:17].C(OC(N1CCC[C@@H]1C(C1C2C(=CC=C(Br)C=2)NC=1)=O)=O)C1C=CC=CC=1>>[Br:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][CH:6]=[C:5]2[CH2:11][CH2:12][N:13]([CH3:14])[CH3:17]

Participants

3

Reactant 2

HCID 11185464(R)-5-Bromo-3-(1-methyl-2-pyrrolidinyl methyl)-1H-indoleHCID 11224090Phenylmethyl (2R)-2-((5-bromo-1H-indol-3-yl)carbonyl)-1-pyrrolidinecarboxylate

Product 1

HCID 3602525-Bromo-N,N-Dimethyltryptamine

Procedure

(R)-5-Bromo-3-[(N-methylpyrrolidin-2-yl)methyl] 1 H-indole: (63%) from (R)-3-(N-benzyloxycarbonylpyrrolidin-2-ylcarbonyl)-5-bromo-1H-indole (Example 1a).

Sources & evidence

ORD record
ord-b24bbcac251648679e5b8de1a0495c62
Source dataset
uspto-grants-2001_12
Patent number
US06329390B1

Reaction notes

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