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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2269020Generated: October 30, 2026

Ammonia → HCID 178458945, compound

https://huagongshe.com/reaction/2269020

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAmmoniaHCID 222—
Reactant6-Amino-9-benzyl-8-methoxy-2-propoxypurineHCID 10881541—
SolventHydrochloric AcidHCID 313—
ProductHCID 178458945HCID 17845894583%

Reaction Steps

6-Amino-9-benzyl-8-methoxy-2-propoxypurine (75 mg, 0.24 mmol) in concentrated hydrochloric acid (15 ml) was stirred for 3 hours at room temperature. The reaction mixture was made basic with 28% aqueous ammonia, and the resulting crystals were filtered and washed with water to give the subject compound (59 mg, yield 83%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06329381B1
Source datasetuspto-grants-2001_12
ORD IDord-a51b6313541d4a3194878f1efa76d072
Source noteuspto-grants-2001_12