HuagongsheHuagongshe Chemistry Print Report · For research reference only
Oxalyl chloride → 3-Chloro-2,4-difluorobenzoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Reactant | 3-Chloro-2,4-difluorobenzoic acid | HCID 2773532 | — |
| Catalyst | Dimethylformamide | HCID 6228 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 3-Chloro-2,4-difluorobenzoyl chloride | HCID 2773538 | — |
Reaction Steps
A quantity of 6.0 g of 3-chloro-2,4-difluorobenzoic acid is suspended in 20 ml of dichloromethane. A quantity of 2.99 ml of oxalyl chloride and 2 drops of DMF are then added. The suspension is stirred at room temperature overnight and the desired product is collected after evaporation of the solvent.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06329391B1 |
| Source dataset | uspto-grants-2001_12 |
| ORD ID | ord-8db39c1dcf4a4ce1a7e0bfb2622b179a |
| Source note | uspto-grants-2001_12 |