(2S, 3S)-3-(5-(1,1-Difluoroethyl)-2-(trifluoromethoxy)benzyl)amino-2-phenylpiperidine → HCID 69712392, compound

HRID 2269256Notes

Reaction equation

HRID 2269256 reaction equation
C(OC([N:8]1[CH2:13][CH2:12][CH2:11][C@H:10]([NH:14][CH2:15][C:16]2[CH:21]=[C:20]([C:22]([F:25])([F:24])[CH3:23])[CH:19]=[CH:18][C:17]=2[O:26][CH3:27])[C@@H:9]1[C:28]1[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=1)=O)(C)(C)C.FC(C1C=CC(OC(F)(F)F)=C(C=1)CN[C@H]1CCCN[C@H]1C1C=CC=CC=1)(F)C>>[F:24][C:22]([C:20]1[CH:19]=[CH:18][C:17]([O:26][CH3:27])=[C:16]([CH:21]=1)[CH2:15][NH:14][C@H:10]1[CH2:11][CH2:12][CH2:13][NH:8][C@H:9]1[C:28]1[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=1)([F:25])[CH3:23]

Participants

3

Reactant 2

HCID 57090611(2S, 3S)-3-(5-(1,1-Difluoroethyl)-2-(trifluoromethoxy)benzyl)amino-2-phenylpiperidineHCID 86757654HCID 86757654, compound

Product 1

HCID 69712392HCID 69712392, compound

Procedure

This compound was prepared from Compound 35 in the same manner of Compound 27

Sources & evidence

ORD record
ord-ffae848200c54bc4b479dc730342bd16
Source dataset
uspto-grants-2001_12
Patent number
US06329396B1

Reaction notes

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