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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2269264Generated: October 30, 2026

(2S,3S)-3-(2-Methoxy-5-(2,2,2-trifluoroethyl)benzyl)amino-2-phenylpiperidine → (2S,3S)-3-(2-Methoxy-5-(2,2,2-trifluoroethyl)benzyl)amino-2-phenylpiperidine dihydrochloride

https://huagongshe.com/reaction/2269264

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2S,3S)-3-(2-Methoxy-5-(2,2,2-trifluoroethyl)benzyl)amino-2-phenylpiperidineHCID 15549737—
Reactant(2S,3S)-3-(5-(1,1-Difluoroethyl)-2-(trifluoromethoxy)benzyl)amino-2-phenylpiperidine dihydrochlorideHCID 86757653—
Product(2S,3S)-3-(2-Methoxy-5-(2,2,2-trifluoroethyl)benzyl)amino-2-phenylpiperidine dihydrochlorideHCID 70000775—

Reaction Steps

This compound was prepared from Compound 48 in the same manner of Compound 28.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06329396B1
Source datasetuspto-grants-2001_12
ORD IDord-847b584de5984139ab8f8edb5d427c6c
Source noteuspto-grants-2001_12