HRID2269267

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CC(C)(C)OC(=O)N1CCC[C@H](N)[C@@H]1c1ccccc1

HCID11311934

未命名化合物

结构：COc1ccc(C(C(F)(F)F)C(F)(F)F)cc1CN[C@H]1CCCN(C(=O)OC(C)(C)C)[C@H]1c1ccccc1

HCID15549735

未命名化合物

HCID18677647

未命名化合物

PRODUCTS

生成物

结构：COc1ccc(C(C)(C)C#CC(F)(F)F)cc1CN[C@H]1CCCN(C(=O)OC(C)(C)C)[C@H]1c1ccccc1

HCID70001735

未命名化合物

PROCEDURE

实验过程

This compound was prepared from Compound 58 and Compound 12 in the same manner of Compound 13.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-57e726f24b4745bbaf70bccce26ffde5
来源数据集: uspto-grants-2001_12
DOI: 10.6084/m9.figshare.5104873.v1
专利: US06329396B1
来源说明: uspto-grants-2001_12

反应 SMILES

[CH3:1][C:2]([C:10]1[CH:11]=[CH:12][C:13]([O:18][CH3:19])=[C:14]([CH:17]=1)[CH:15]=O)([CH3:9])[C:3]#[C:4][C:5]([F:8])([F:7])[F:6].[NH2:20][C@H:21]1[CH2:26][CH2:25][CH2:24][N:23]([C:27]([O:29][C:30]([CH3:33])([CH3:32])[CH3:31])=[O:28])[C@H:22]1[C:34]1[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=1.C(OC(N1CCC[C@H](NCC2C=C(C(C(F)(F)F)C(F)(F)F)C=CC=2OC)[C@@H]1C1C=CC=CC=1)=O)(C)(C)C>>[C:30]([O:29][C:27]([N:23]1[CH2:24][CH2:25][CH2:26][C@H:21]([NH:20][CH2:15][C:14]2[CH:17]=[C:10]([C:2]([CH3:9])([CH3:1])[C:3]#[C:4][C:5]([F:8])([F:7])[F:6])[CH:11]=[CH:12][C:13]=2[O:18][CH3:19])[C@@H:22]1[C:34]1[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=1)=[O:28])([CH3:33])([CH3:31])[CH3:32]