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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2269277Generated: October 30, 2026

(S,3S)-3-[5-(1,1-Dimethyl-2,2,2-trifluoroethyl)-2-methoxybenzylamino]-2-phenylpiperidine → (2S,3S)-3-[5-(1,1-Dimethyl-2,2,2-trifluoroethyl)-2-methoxybenzylamino]-2-phenylpiperidine dihydrochloride

https://huagongshe.com/reaction/2269277

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(S,3S)-3-[5-(1,1-Dimethyl-2,2,2-trifluoroethyl)-2-methoxybenzylamino]-2-phenylpiperidineHCID 44433394—
Reactant(2S,3S)-3-(5-(1,1-Difluoroethyl)-2-(trifluoromethoxy)benzyl)amino-2-phenylpiperidine dihydrochlorideHCID 86757653—
Product(2S,3S)-3-[5-(1,1-Dimethyl-2,2,2-trifluoroethyl)-2-methoxybenzylamino]-2-phenylpiperidine dihydrochlorideHCID 70000497—

Reaction Steps

This compound was prepared from Compound 73 in the same manner of Compound 28.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06329396B1
Source datasetuspto-grants-2001_12
ORD IDord-6c8d0faeeaed4f43942e5e2a1ae31fbe
Source noteuspto-grants-2001_12