HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2S,3S)-3-Amino-1-tert-butoxycarbonyl-2-phenylpiperidine → (2S,3S)-1-tert-Butoxycarbonyl-3-[5-[2,2-difluoro-1-(trifluoromethyl)ethenyl]-2-methoxybenzyl]amino-2-phenylpiperidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2S,3S)-3-Amino-1-tert-butoxycarbonyl-2-phenylpiperidine | HCID 11311934 | — |
| Reactant | (2S, 3S)-1-tert-Butoxycarbonyl-2-phenyl-3-(5-(2,2,2-trifluoro-1-(trifluoromethyl)ethyl)-2-methoxybenzyl)aminopiperidine | HCID 15549735 | — |
| Reactant | 5-[2,2-Difluoro-1-(trifluoromethyl)ethenyl]-2-methoxybenzaldehyde | HCID 18677596 | — |
| Product | (2S,3S)-1-tert-Butoxycarbonyl-3-[5-[2,2-difluoro-1-(trifluoromethyl)ethenyl]-2-methoxybenzyl]amino-2-phenylpiperidine | HCID 70001040 | — |
Reaction Steps
This compound was prepared from Compound 79 and Compound 12 in the same manner of Compound 13.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06329396B1 |
| Source dataset | uspto-grants-2001_12 |
| ORD ID | ord-e4273ecec43a4963bdf74cdb42942543 |
| Source note | uspto-grants-2001_12 |