2,4-Dimethoxybenzaldehyde → 1-(2,4-Dimethoxyphenyl)-2,2,2-trifluoroethanol

HRID 2269281Notes

Reaction equation

HRID 2269281 reaction equation
[CH3:1][O:2][C:3]1[CH:10]=[C:9]([O:11][CH3:12])[CH:8]=[CH:7][C:4]=1[CH:5]=[O:6].OC1([C:25]([F:28])([F:27])[F:26])C2C(=CC(OC)=CC=2)CC1>>[CH3:1][O:2][C:3]1[CH:10]=[C:9]([O:11][CH3:12])[CH:8]=[CH:7][C:4]=1[CH:5]([OH:6])[C:25]([F:28])([F:27])[F:26]

Participants

3

Reactant 2

HCID 691752,4-DimethoxybenzaldehydeHCID 186776465-methoxy-1-(trifluoromethyl)-2,3-dihydro-1H-inden-1-ol

Product 1

HCID 129134811-(2,4-Dimethoxyphenyl)-2,2,2-trifluoroethanol

Procedure

This compound was prepared from 2,4-dimethoxybenzaldehyde in the same manner of Compound 62.

Sources & evidence

ORD record
ord-27114ea1e1714fb6a70fb988d3662613
Source dataset
uspto-grants-2001_12
Patent number
US06329396B1

Reaction notes

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