1-(1-Bromo-2,2,2-trifluoroethyl)-4-methoxybenzene → 1-(2,4-Dimethoxyphenyl)-2,2,2-trifluoroethyl bromide

HRID 2269282Notes

Reaction equation

HRID 2269282 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[C:7]([O:9][CH3:10])[CH:6]=[CH:5][C:4]=1[CH:11](O)[C:12]([F:15])([F:14])[F:13].COC1C=CC(C([Br:30])C(F)(F)F)=CC=1>>[CH3:1][O:2][C:3]1[CH:8]=[C:7]([O:9][CH3:10])[CH:6]=[CH:5][C:4]=1[CH:11]([Br:30])[C:12]([F:15])([F:14])[F:13]

Participants

3

Reactant 2

HCID 114485791-(1-Bromo-2,2,2-trifluoroethyl)-4-methoxybenzeneHCID 129134811-(2,4-Dimethoxyphenyl)-2,2,2-trifluoroethanol

Product 1

HCID 186776511-(2,4-Dimethoxyphenyl)-2,2,2-trifluoroethyl bromide

Procedure

This compound was prepared from Compound 82 in the same manner of Compound 44.

Sources & evidence

ORD record
ord-c09fb138cbeb4282a2cf14029d13ba66
Source dataset
uspto-grants-2001_12
Patent number
US06329396B1

Reaction notes

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