1-Methoxy-4-(2,2,2-trifluoroethyl)benzene → 2,4-Dimethoxy-1-(2,2,2-trifluoroethyl)benzene

HRID 2269283Notes

Reaction equation

HRID 2269283 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[C:7]([O:9][CH3:10])[CH:6]=[CH:5][C:4]=1[CH:11](Br)[C:12]([F:15])([F:14])[F:13].COC1C=CC(CC(F)(F)F)=CC=1>>[CH3:1][O:2][C:3]1[CH:8]=[C:7]([O:9][CH3:10])[CH:6]=[CH:5][C:4]=1[CH2:11][C:12]([F:13])([F:15])[F:14]

Participants

3

Reactant 2

HCID 155526911-Methoxy-4-(2,2,2-trifluoroethyl)benzeneHCID 186776511-(2,4-Dimethoxyphenyl)-2,2,2-trifluoroethyl bromide

Product 1

HCID 186775802,4-Dimethoxy-1-(2,2,2-trifluoroethyl)benzene

Procedure

This compound was prepared from Compound 83 in the same manner of Compound 45.

Sources & evidence

ORD record
ord-dc66ed656c554027875716199a53cbd4
Source dataset
uspto-grants-2001_12
Patent number
US06329396B1

Reaction notes

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