1,1,1,3,3,3-Hexafluoro-2-(4-methoxyphenyl)propan-2-ol → 2-Methoxy-5-(2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl)benzaldehyde

HRID 2269290Notes

Reaction equation

HRID 2269290 reaction equation
[F:1][C:2]([F:18])([F:17])[C:3]([C:9]1[CH:14]=[CH:13][C:12]([O:15][CH3:16])=[CH:11][CH:10]=1)([OH:8])[C:4]([F:7])([F:6])[F:5].FC(F)(F)C(C1C=CC(OC)=C(C=1)[CH:31]=[O:32])C(F)(F)F>>[CH3:16][O:15][C:12]1[CH:13]=[CH:14][C:9]([C:3]([OH:8])([C:4]([F:6])([F:5])[F:7])[C:2]([F:17])([F:18])[F:1])=[CH:10][C:11]=1[CH:31]=[O:32]

Participants

3

Reactant 2

HCID 186775911,1,1,3,3,3-Hexafluoro-2-(4-methoxyphenyl)propan-2-olHCID 186776145-(2,2,2-Trifluoro-1-(trifluoromethyl)ethyl)-2-methoxybenzaldehyde

Product 1

HCID 186775762-Methoxy-5-(2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl)benzaldehyde

Procedure

This compound was prepared from Compound 99 in the same manner of Compound 9.

Sources & evidence

ORD record
ord-1e1560fd7d0b432f9a2d2321a95b7558
Source dataset
uspto-grants-2001_12
Patent number
US06329396B1

Reaction notes

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