HCID 20712368, compound → HCID 44394383, compound

HRID 2269326Notes

Reaction equation

HRID 2269326 reaction equation
C(OC(C1C(O)(CC)CCCN1S(C1C=CC(OCC2C=CC(F)=CC=2)=CC=1)(=O)=O)=O)(C)(C)C.[OH:35][NH:36][C:37]([CH:39]1[C:44]([OH:47])([CH2:45][CH3:46])[CH2:43][CH2:42][CH2:41][N:40]1[S:48]([C:51]1[CH:56]=[CH:55][C:54]([O:57][CH2:58][C:59]2[CH:64]=[CH:63][C:62]([F:65])=[CH:61][CH:60]=2)=[CH:53][CH:52]=1)(=[O:50])=[O:49])=[O:38]>>[OH:35][NH:36][C:37]([C@H:39]1[C@@:44]([OH:47])([CH2:45][CH3:46])[CH2:43][CH2:42][CH2:41][N:40]1[S:48]([C:51]1[CH:56]=[CH:55][C:54]([O:57][CH2:58][C:59]2[CH:64]=[CH:63][C:62]([F:65])=[CH:61][CH:60]=2)=[CH:53][CH:52]=1)(=[O:50])=[O:49])=[O:38]

Participants

3

Reactant 2

HCID 20712368HCID 20712368, compoundHCID 54045028HCID 54045028, compound

Product 1

HCID 44394383HCID 44394383, compound

Procedure

Using the methods of Example 4, 1-[4-(4-fluoro-benzyloxy)-benzenesulfonyl]-3-hydroxy-3-ethyl-piperidine-2-carboxylic acid tert-butyl ester was converted to 1-[4-(4-Fluoro-benzyloxy)-benzenesulfonyl]-3-hydroxy-3-ethyl-piperidine-2-carboxylic acid hydroxyamide.

Sources & evidence

ORD record
ord-e00fcc859f404fd988946187bc047b6a
Source dataset
uspto-grants-2001_12
Patent number
US06329397B1

Reaction notes

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