2-Methylcyclohexanone → HCID 12050052, compound

Participants

Reaction Steps

This compound was prepared by the procedure of Example 1 using 4-bromo-phenyl hydrazine hydrochloride (2.0 g, 8.95 mmol) and 2-methylcyclohexanone (1.0 g, 8.95 mmol). The subtitled compound (1.5 g, 65%) was obtained as a yellow oil: 1H NMR (CDCl3)δ 1.26 (s, 3H), 1.38-1.46 (m, 4H), 1.56-1.68 (m, 4H), 3.4 (t,J =4.4 Hz, 1H), 3.6 (br s, 1H), 6.53 (d,J=8 Hz, 1H), 7.08 (d,J=2.0 Hz, 1H), 7.09 (dd,J=8.0, 2.0 Hz, 1H); 13C-NMR (CDCl3)δ 21.45, 21.87 (t), 23.96 (q), 27.92, 35.32 (t), 43.56 (s), 66.65 (d), 110.73 (s), 111.88, 125.25, 129.99 (d), 142.17, 149.03 (s); MS (EI) m/z 268, 270 (M+H)+.

Provenance & Evidence