HCID 86757662, compound → HCID 57062265, compound

Participants

Reaction Steps

A solution of ethyl (2R,3R)-2-[(2E)-3-phenyl-2-propen-1-yl]-3-hydroxyhexanoate (1.76 g, 6.38 mmol) in 30 mL of EtOAc is treated with 200 mg of 10% palladium on carbon. The resulting suspension is repeatedly evacuated and purged with a hydrogen balloon, then stirred under 1 atmosphere pressure of hydrogen gas for 6 h. The catalyst is filtered and the filtrate is concentrated in vacuo to provide ethyl (2R,3R)-2-(3-phenyl-1-propyl)-3-hydroxyhexanoate as an oil (1.70 g, 96% yield).

Provenance & Evidence