3-Cyclobutene-1,2-dione, 3,4-dimethoxy- → HCID 18334092, compound

HRID 2269376Notes

Reaction equation

HRID 2269376 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([CH:9]([NH:17][CH2:18][CH2:19][C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)[C:10]2[CH:11]=[C:12]([NH2:16])[CH:13]=[CH:14][CH:15]=2)=[CH:5][CH:4]=1.[CH3:26][O:27][C:28]1[C:29](=O)[C:30](=[O:34])[C:31]=1[O:32]C>CO>[CH3:26][O:27][C:28]1[C:31](=[O:32])[C:30](=[O:34])[C:29]=1[NH:16][C:12]1[CH:13]=[CH:14][CH:15]=[C:10]([CH:9]([C:6]2[CH:5]=[CH:4][C:3]([O:2][CH3:1])=[CH:8][CH:7]=2)[NH:17][CH2:18][CH2:19][C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)[CH:11]=1

Participants

4

Reactant 2

HCID 1232273-Cyclobutene-1,2-dione, 3,4-dimethoxy-HCID 18347073HCID 18347073, compound

Product 1

HCID 18334092HCID 18334092, compoundYield 81.2%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

In a similar manner to that described in Example (1c), a solution of 3-[(4-methoxyphenyl)-(2-phenylethylamino)methyl]phenylamine (1.74 g) [prepared as described in step (b) above] in methanol (40 ml) and 3,4-dimethoxy-3-cyclobutene-1,2-dione (776 mg) were reacted, to afford the title compound (1.88 g) as yellow foamy solid.

Sources & evidence

ORD record
ord-74f177ce6d9b4774bf4bf69f6e6f4cbe
Source dataset
uspto-grants-2001_12
Patent number
US06329405B1

Reaction notes

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