Ammonia → HCID 18334247, compound

HRID 2269382Notes

Reaction equation

HRID 2269382 reaction equation
C[O:2][C:3]1[C:4](=[O:40])[C:5](=O)[C:6]=1[NH:7][C:8]1[CH:13]=[CH:12][CH:11]=[C:10]([CH:14]([C:31]2[CH:36]=[CH:35][C:34]([O:37][CH3:38])=[CH:33][CH:32]=2)[NH:15][CH2:16][CH2:17][CH:18]([C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=2)[C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)[CH:9]=1.[NH3:41]>C(O)C>[NH2:41][C:5]1[C:4](=[O:40])[C:3](=[O:2])[C:6]=1[NH:7][C:8]1[CH:13]=[CH:12][CH:11]=[C:10]([CH:14]([C:31]2[CH:32]=[CH:33][C:34]([O:37][CH3:38])=[CH:35][CH:36]=2)[NH:15][CH2:16][CH2:17][CH:18]([C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)[C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=2)[CH:9]=1

Participants

4

Reactant 2

HCID 222AmmoniaHCID 18347087HCID 18347087, compound

Product 1

HCID 18334247HCID 18334247, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

In a similar maiser to that described in Example (1d), 3-methoxy-4-{3-[(4-methoxyphenyl)-(3,3-diphenylpropylamino)methyl]phenylamino}-3-cyclobutene-1,2-dione (1.86 g) [prepared as described in step (c) above] and a solution of ammonia in ethanol (2N, 7 ml) were reacted, to give the title compound (1.36 g) as a pale yellow solid.

Sources & evidence

ORD record
ord-18c1f5fc79b2489e8a74b6fe73aa3a5b
Source dataset
uspto-grants-2001_12
Patent number
US06329405B1

Reaction notes

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