Ammonia → HCID 18334255, compound

HRID 2269385Notes

Reaction equation

HRID 2269385 reaction equation
C[O:2][C:3]1[C:4](=[O:39])[C:5](=O)[C:6]=1[NH:7][C:8]1[CH:13]=[CH:12][CH:11]=[C:10]([CH:14]([C:30]2[CH:35]=[CH:34][C:33]([O:36][CH3:37])=[CH:32][CH:31]=2)[NH:15][CH2:16][CH:17]([C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=2)[C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[CH:9]=1.[NH3:40]>C(O)C>[NH2:40][C:5]1[C:4](=[O:39])[C:3](=[O:2])[C:6]=1[NH:7][C:8]1[CH:13]=[CH:12][CH:11]=[C:10]([CH:14]([C:30]2[CH:31]=[CH:32][C:33]([O:36][CH3:37])=[CH:34][CH:35]=2)[NH:15][CH2:16][CH:17]([C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=2)[CH:9]=1

Participants

4

Reactant 2

HCID 222AmmoniaHCID 18347043HCID 18347043, compound

Product 1

HCID 18334255HCID 18334255, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

In a similar manner to that described in Example (1d), 3-methoxy-4-{3-[(4-methoxyphenyl)-(2,2-diphenylethylamino)methyl]phenylamino}-3-cyclobutene-1,2-dione (1.35 g) [prepared as described in step (c) above] and a solution of ammonia in ethanol (2N, 5.2 ml) were reacted, to give the title compound (1.36 g) as a pale yellow solid.

Sources & evidence

ORD record
ord-e8a47dc13eb04b368de265df1545e7f6
Source dataset
uspto-grants-2001_12
Patent number
US06329405B1

Reaction notes

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