反应详情

In a similar manner to that described in Example (15b), a solution of N-[(3-nitrophenyl)-(4-fluorophenyl)methyl]-N-[1-(3,4-difluorophenyl)ethyl]amine (3.0 g) [prepared as described in step (a) above] in methanol (10 ml), nickel chloride hexahydrate (3.69 g) and sodium borohydride (1.24 g) were reacted, and the reaction mixture was purified to afford isomer A of the title compound (630 mg) as a pale yellow oil and isomer B of the title compound (580 mg) as a pale yellow oil.

1. customthe reaction mixture was purified