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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2269408Generated: October 30, 2026

Sodium borohydride → HCID 70189187, compound

https://huagongshe.com/reaction/2269408

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium borohydrideHCID 4311764—
ReactantHCID 70189286HCID 70189286—
CatalystDichloronickel;hexahydrateHCID 11791229—
SolventMethanolHCID 887—
ProductHCID 70189187HCID 7018918776.6%

Reaction Steps

In a similar manner to that described in Example (1b), a solution of N-[(3-nitrophenyl)-(4-methoxyphenyl)methyl]-N-[(R)-1-cyclohexylethyl]amine (2.60 g) [prepared as described in step (a) above] in methanol (50 ml), nickel chloride hexahydrate (3.35 g) and sodium borohydride (1.12 g) were reacted, to afford the title compound (1.83 g) as a colorless oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06329405B1
Source datasetuspto-grants-2001_12
ORD IDord-f261b83771dd4129b364af789c7884f8
Source noteuspto-grants-2001_12