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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2269409Generated: October 30, 2026

Sodium borohydride → HCID 70189109, compound

https://huagongshe.com/reaction/2269409

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium borohydrideHCID 4311764—
ReactantHCID 70190089HCID 70190089—
CatalystDichloronickel;hexahydrateHCID 11791229—
SolventMethanolHCID 887—
ProductHCID 70189109HCID 70189109100.2%

Reaction Steps

In a similar manner to that described in Example (1b), a solution of N-[(3-nitrophenyl)-(4-methoxyphenyl)methyl]-N-[(S)-1-cyclohexylethyl]amine (2.63 g) [prepared as described in step (a) above] in methanol (50 ml), nickel chloride hexahydrate (3.39 g) and sodium borohydride (1.14 g) were reacted, to afford the title compound (2.42 g) as a yellow oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06329405B1
Source datasetuspto-grants-2001_12
ORD IDord-9ebd96a1e4124329b69ff007184d90b3
Source noteuspto-grants-2001_12