Sodium borohydride → HCID 18347066, compound

Participants

Reaction Steps

In a similar manner to that described in Example (1b), a solution of N-[(4-nitrophenyl)-(4-methoxyphenyl)methyl]-N-[1-(3,4-difluorophenyl)ethyl]amine (3.20 g) [prepared as described in step (a) above] in methanol (60 ml), nickel chloride hexahydrate (3.82 a) and sodium borohydride (1.21 g) were reacted and purified, to afford the less polar isomer A (720 mg) as a pale yellow oil and the more polar isomer B (805 mg) as a pale yellow oil of the title compound.

Provenance & Evidence