Stannous Chloride → HCID 88201970, compound

Participants

Reaction Steps

A mixture of isomer A of 4-methoxyphenyl 3-nitrophenyl ketone O-benzyloxime (974 mg) [prepared as described in step (a) above] and tin (II) chloride (2.55 g) in ethanol (30 ml) was heated under reflux for 1 hour. After removal of the ethanol by evaporation, the residue was diluted with ethyl acetate. The ethyl acetate was washed with a 5N aqueous solution of sodium hydroxide, with water and then with a saturated aqueous solution of sodium chloride. It was then dried over anhydrous magnesium sulfate and evaporated under reduced pressure, to afford isomer A of the title compound (893 mg) as a yellow oil.

Provenance & Evidence