Stannous Chloride → HCID 18334172, compound

HRID 2269428Notes

Reaction equation

[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([CH:9]([C:21]2[CH:26]=[CH:25][CH:24]=[C:23]([N+:27]([O-])=O)[CH:22]=2)[NH:10][C:11](=[O:20])[CH:12]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[CH3:13])=[CH:5][CH:4]=1.[Sn](Cl)[Cl:31]>>[ClH:31].[NH2:27][C:23]1[CH:22]=[C:21]([CH:9]([C:6]2[CH:5]=[CH:4][C:3]([O:2][CH3:1])=[CH:8][CH:7]=2)[NH:10][C:11](=[O:20])[CH:12]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[CH3:13])[CH:26]=[CH:25][CH:24]=1

Participants

Reactant 2

HCID 24479Stannous Chloride

HCID 18347107HCID 18347107, compound

Product 1

HCID 18334172HCID 18334172, compoundYield 81.4%

Procedure

In a similar manner to that described in Example (47b), N-[(4-methoxyphenyl)-(3-nitrophenyl)methyl]-2-phenylpropionamide (2.37 g) [prepared as described in step (a) above] and tin (II) chloride (5.76 g) were reacted, to afford the title compound (1.96 g) as a white solid.

Workup

customwere reacted

Sources & evidence

ORD record: ord-d5fa1283d29c4c4188872cf622c5f1c0
Source dataset: uspto-grants-2001_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06329405B1

Reaction notes

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