Sodium borohydride → HCID 18334219, compound

HRID 2269466Notes

Reaction equation

HRID 2269466 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH:8]([NH:10][CH:11]([C:21]2[CH:26]=[CH:25][C:24]([O:27][CH3:28])=[CH:23][CH:22]=2)[C:12]2[CH:17]=[CH:16][CH:15]=[C:14]([N+:18]([O-])=O)[CH:13]=2)[CH3:9])[CH:5]=[CH:6][CH:7]=1.[BH4-].[Na+]>O.O.O.O.O.O.[Ni](Cl)Cl>[Cl:1][C:2]1[CH:3]=[C:4]([CH:8]([NH:10][CH:11]([C:21]2[CH:22]=[CH:23][C:24]([O:27][CH3:28])=[CH:25][CH:26]=2)[C:12]2[CH:13]=[C:14]([NH2:18])[CH:15]=[CH:16][CH:17]=2)[CH3:9])[CH:5]=[CH:6][CH:7]=1

Participants

4

Reactant 2

HCID 4311764Sodium borohydrideHCID 18347129HCID 18347129, compound

Product 1

HCID 18334219HCID 18334219, compoundYield 89.5%

Reagents, catalysts & solvents 1

HCID 11791229Dichloronickel;hexahydrateCatalyst

Procedure

Following a similar procedure to that described in Example (1b), 2.60 g of N-[1-(3-chlorophenyl)ethyl]-N-[(4-methoxyphenyl)-(3-nitrophenyl)methyl]amine [prepared as described in step (a) above], 3.11 g of nickel chloride hexahydrate and 1.04 g of sodium borohydride were reacted, to obtain 2.15 g of the title compound as a yellow oil.

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-63e91bd393ae4e0a9ede7488f96f9cfe
Source dataset
uspto-grants-2001_12
Patent number
US06329405B1

Reaction notes

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