Sodium borohydride → HCID 18334114, compound

HRID 2269467Notes

Reaction equation

HRID 2269467 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([CH:9]([C:23]2[CH:28]=[CH:27][CH:26]=[C:25]([N+:29]([O-])=O)[CH:24]=2)[NH:10][CH:11]([C:13]2[CH:18]=[CH:17][CH:16]=[C:15]([C:19]([F:22])([F:21])[F:20])[CH:14]=2)[CH3:12])=[CH:5][CH:4]=1.[BH4-].[Na+]>O.O.O.O.O.O.[Ni](Cl)Cl>[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]([CH:9]([NH:10][CH:11]([C:13]2[CH:18]=[CH:17][CH:16]=[C:15]([C:19]([F:20])([F:22])[F:21])[CH:14]=2)[CH3:12])[C:23]2[CH:24]=[C:25]([NH2:29])[CH:26]=[CH:27][CH:28]=2)=[CH:7][CH:8]=1

Participants

4

Reactant 2

HCID 4311764Sodium borohydrideHCID 18347136HCID 18347136, compound

Product 1

HCID 18334114HCID 18334114, compoundYield 98.1%

Reagents, catalysts & solvents 1

HCID 11791229Dichloronickel;hexahydrateCatalyst

Procedure

Following a similar procedure to that described in Example (1b), 2.85 g of N-[(4-methoxyphenyl)-(3-nitrophenyl)methyl]-N-[1-(3-trifluoromethylphenyl)ethyl]amine [prepared as described in step (a) above], 3.15 g of nickel chloride hexahydrate and 1.05 g of sodium borohydride were reacted, to obtain 2.60 g of the title compound as a yellow oil.

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-804b15f34dc34f9fa9cefe4c14ec65bd
Source dataset
uspto-grants-2001_12
Patent number
US06329405B1

Reaction notes

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