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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2269485Generated: October 25, 2026

(3-Nitrophenyl)-thiophen-2-ylmethanone → N-[1-(3,4-Difluorophenyl)ethyl]-N-[(3-nitrophenyl)-(thiophen-2-yl)methyl}amine

https://huagongshe.com/reaction/2269485

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(3-Nitrophenyl)-thiophen-2-ylmethanoneHCID 348407—
Reactant1-(3,4-Difluorophenyl)ethanamineHCID 3815974—
ProductN-[1-(3,4-Difluorophenyl)ethyl]-N-[(3-nitrophenyl)-(thiophen-2-yl)methyl}amineHCID 1834706995%

Reaction Steps

Following a similar procedure to that described in Example (1a), 3.03 g of 3-nitrophenyl thiophen-2-yl ketone and 2.52 g of 1-(3,4-difluorophenyl)ethylamine were reacted, to obtain 4.62 g of the title compound as a reddish orange oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06329405B1
Source datasetuspto-grants-2001_12
ORD IDord-7247e6c2e9d94f76889dc03f811c4f4f
Source noteuspto-grants-2001_12