Sodium borohydride → HCID 70190188, compound

Participants

Reaction Steps

Following a similar reaction, separation and purification procedure to that described in Example (59b), 2.38 g of N-[(4-clorophenyl)-(3-nitrophenyl)methyl]-N-[(R)-1-(3,4,5-trifluorophenyl)ethyl]amine [prepared as described in step (a) above], 2.69 g of nickel chloride hexahydrate and 866 mg of sodium borohydride were reacted, to obtain 942 mg of isomer A and 663 mg of isomer B of the title compound, each as a colorless oil.

Provenance & Evidence