Sodium borohydride → HCID 70189275, compound

Participants

Reaction Steps

Following a similar reaction, separation and purification procedure to that described in Example (59b), 2.46 g of N-[(4-fluorophenyl)-(3-nitrophenyl)methyl]-N-[(R)-1-(3,4,5-trifluorophenyl)ethyl]amine [prepared as described in step (a) above], 2.90 g of nickel chloride hexahydrate and 927 mg of sodium borohydride were reacted, to obtain 760 mg of isomer A and 716 mg of isomer B of the title compound, each as a colorless oil.

Provenance & Evidence