Sodium borohydride → HCID 70188112, compound

Participants

Reaction Steps

Following a similar reaction, separation and purification procedure to that described in Example (59b), 8.32 g of N-[(4-methoxyphenyl)-(3-nitrophenyl)methyl]-N-[(R)-1-(naphthalen-1-yl)ethyl]amine [prepared as described in step (a) above], 9.51 g of nickel chloride hexahydrate and 3.03 g of sodium borohydride were reacted, to obtain 1.15 g of isomer A and 462 mg of isomer B of the title compound, each as a colorless oil.

Provenance & Evidence