HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Propanol → 3,4-Dichloro-α-oxobenzeneacetonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Propanol | HCID 1031 | — |
| Reactant | HCID 178511375 | HCID 178511375 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | 3,4-Dichloro-α-oxobenzeneacetonitrile | HCID 9942422 | — |
| Product | HCID 15332575 | HCID 15332575 | — |
Reaction Steps
The title compound was prepared as in Example 2(a) from 3,4-dichlorobenzoyl cyanide amidinohydrazone obtained in Example 5. The solvent for the ring closure was a mixture of 1-propanol and dimethyl sulfoxide (11). Total yield (from 3,4-dichlorobenzoyl cyanide): 76%; m.p. 222-224° C. (uncorrected).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06329521B2 |
| Source dataset | uspto-grants-2001_12 |
| ORD ID | ord-8906e27b682a47089df44c86ffdcf4bf |
| Source note | uspto-grants-2001_12 |