HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Propanol → 4-Chlorobenzoyl cyanide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Propanol | HCID 1031 | — |
| Reactant | HCID 178511373 | HCID 178511373 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | 4-Chlorobenzoyl cyanide | HCID 9834051 | — |
| Product | HCID 21814736 | HCID 21814736 | — |
Reaction Steps
The title compound was prepared as in Example 2(a) from 4-chlorobenzoyl cyanide amidinohydrazone obtained in Example 7. The solvent for the ring closure was a mixture of 1-propanol and dimethyl sulfoxide (4:1). Total yield (from 4-chlorobenzoyl cyanide): 72%; m.p. 219-221° C. (uncorrected).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06329521B2 |
| Source dataset | uspto-grants-2001_12 |
| ORD ID | ord-d1943596a26641c1aae2b12abfaee98e |
| Source note | uspto-grants-2001_12 |