HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tert-Butylamine → HCID 131722958, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tert-Butylamine | HCID 6385 | — |
| Reactant | 1-Hydroxybenzotriazole | HCID 75771 | — |
| Reactant | 1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochloride | HCID 2723939 | — |
| Reactant | Boc-Hyp(Bzl)-OH | HCID 11860409 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 131722958 | HCID 131722958 | — |
Reaction Steps
In a DMF solution containing 100 mg of Boc-Hyp(Bzl)-OH, 33 μl of t-butylamine, 48 mg of HOBt and 71 mg of EDC hydrochloride were added and the resultant mixture was stirred for 14 hr. The reaction mixture was treated similarly to that in Example 33 (Process 3) to give 88 mg of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06329502B1 |
| Source dataset | uspto-grants-2001_12 |
| ORD ID | ord-4546b727d2de41cfa81e2a0885d86614 |
| Source note | uspto-grants-2001_12 |