HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2269731Generated: October 29, 2026
O-Phenylenediamine → Ethyl 3-hydroxyquinoxaline-2-carboxylate
https://huagongshe.com/reaction/2269731
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | O-Phenylenediamine | HCID 7243 | — |
| Reactant | 1,3-Diethyl 2-oxopropanedioate | HCID 69105 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | Ethyl 3-hydroxyquinoxaline-2-carboxylate | HCID 248643 | 81.8% |
Reaction Steps
Diethyl ketomalonate (8 g) was added to an ethanol (100 ml) solution of 1,2-phenylenediamine (5 g). The reaction mixture was stirred at 50° C. for 14 hours. The precipitated crystals were filtrated, which was washed with IPE to obtain the entitled compound (8.2 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US06329389B1 |
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| Source dataset | uspto-grants-2001_12 |
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| ORD ID | ord-01d7a3f0a0164db1b73957bdbb1646d4 |
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| Source note | uspto-grants-2001_12 |
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