Acetic Anhydride → HCID 18333093, compound

Participants

Reaction Steps

To a solution of 7-amino-3-(N,N-dimethylamino)methyl-1,2,3,4-tetrahydroquinoline (300 mg) in pyridine (3 ml) was added a solution of acetic anhydride (150 mg) in THF (1 ml) and stirring was continued for 30 minutes. The reaction mixture was purified by alumina column chromatography (eluent; ethyl acetate to ethyl acetate/methanol=20:1) and the resulting crystals were washed with IPE to obtain the entitled compound (275 mg).

Provenance & Evidence