Ethyl 3-(2-aminophenyl)-2-methyl-2-propenate → 3-methylquinolin-2(1H)-one

HRID 2269782Notes

Reaction equation

HRID 2269782 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH:8]=[C:9]([CH3:15])[C:10](OCC)=[O:11]>C(O)C>[CH3:15][C:9]1[C:10](=[O:11])[NH:1][C:2]2[C:3]([CH:8]=1)=[CH:4][CH:5]=[CH:6][CH:7]=2

Participants

3

Reactant 1

HCID 70217004Ethyl 3-(2-aminophenyl)-2-methyl-2-propenate

Product 1

HCID 4409873-methylquinolin-2(1H)-one

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Into 10 ml of ethanol, 0.5 g of (E) ethyl 3-(2-aminophenyl)-2-methyl-2-propenate was dissolved; and, while being stirred, the mixture was irradiated with ultraviolet rays at 256 nm for 48 hours. The reaction liquid was concentrated under a reduced pressure, and the resulting crude crystal was recrystallized from ethanol, whereby the aimed compound was obtained.

Workup

  1. customthe mixture was irradiated with ultraviolet rays at 256 nm for 48 hours
  2. customThe reaction liquid
  3. concentrationwas concentrated under a reduced pressure
  4. customthe resulting crude crystal was recrystallized from ethanol, whereby the aimed compound
  5. customwas obtained

Sources & evidence

ORD record
ord-55c7f97f80fb49068a2a265eec722eb9
Source dataset
uspto-grants-2001_12
Patent number
US06329546B1

Reaction notes

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