HCID 70216867, compound → HCID 18348024, compound

HRID 2269785Notes

Reaction equation

HRID 2269785 reaction equation
[NH2:1][C:2]1[CH:7]=[C:6]([N:8]([CH3:10])[CH3:9])[CH:5]=[CH:4][C:3]=1[CH:11]=[C:12]([CH3:18])[C:13](OCC)=[O:14]>C(O)C>[CH3:9][N:8]([CH3:10])[C:6]1[CH:7]=[C:2]2[C:3]([CH:11]=[C:12]([CH3:18])[C:13](=[O:14])[NH:1]2)=[CH:4][CH:5]=1

Participants

3

Reactant 1

HCID 70216867HCID 70216867, compound

Product 1

HCID 18348024HCID 18348024, compoundYield 98%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

In a 30-ml Erlenmeyer flask made of quartz, 200 mg of (E) ethyl 3-(2-amino-4-dimethylaminophenyl)-2-methyl-2-propenate were dissolved in ethanol; and, while being stirred, the mixture was irradiated with ultraviolet rays at 365 nm for 48 hours. The reaction liquid was concentrated under a reduced pressure, and the resulting crude crystal was recrystallized from ethanol, whereby the aimed compound was obtained (yield: 98%).

Workup

  1. customthe mixture was irradiated with ultraviolet rays at 365 nm for 48 hours
  2. customThe reaction liquid
  3. concentrationwas concentrated under a reduced pressure
  4. customthe resulting crude crystal was recrystallized from ethanol, whereby the aimed compound
  5. customwas obtained (yield: 98%)

Sources & evidence

ORD record
ord-869149ab8eb44e3090c4492193eaecfb
Source dataset
uspto-grants-2001_12
Patent number
US06329546B1

Reaction notes

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