HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diphenyl Ether → 3-(3,4-Dimethyl-benzoyl)-6-methyl-1H-[1,5]naphthyridin-4-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diphenyl Ether | HCID 7583 | — |
| Reactant | 5-Amino-2-methylpyridine | HCID 243313 | — |
| Reactant | 2-(3,4-Dimethyl-benzoyl)-3-methoxy-acrylic acid methyl ester | HCID 66879272 | — |
| Product | 3-(3,4-Dimethyl-benzoyl)-6-methyl-1H-[1,5]naphthyridin-4-one | HCID 57754783 | 22% |
Reaction Steps
Experimental conditions analogous to those described for step 1 of Example 1 were used with 0.50 g (2.01 mmol) 2-(3,4-Dimethyl-benzoyl)-3-methoxy-acrylic acid methyl ester, 0.22 g (2.01 mmol) of 6-Methyl-pyridin-3-ylamine, and 15 mL of diphenyl ether to yield 129 mg of 3-(3,4-Dimethyl-benzoyl)-6-methyl-1H-[1,5]naphthyridin-4-one as a brown solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07557213B2 |
| Source dataset | uspto-grants-2009_07 |
| ORD ID | ord-f916954bb573487591ccb30dc54b5a24 |
| Source note | uspto-grants-2009_07 |