HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cesium carbonate → HCID 86757671, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cesium carbonate | HCID 10796 | — |
| Reactant | HCID 57217334 | HCID 57217334 | — |
| Reactant | HCID 178418634 | HCID 178418634 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 86757671 | HCID 86757671 | 92% |
Reaction Steps
Prepare by the method of Example 1.4 using N,N′-diphenethyl-2-((R)-2-bromo-3-phenylpropionylamino)malonamide (0.11 g, 0.21 mmol), thioacetic acid (0.05 mL, 0.62 mmol), and cesium carbonate (0.10 g, 0.31 mmol) in dimethylformamide (8 mL). Purify by chromatography on silica gel eluting with 1/1 hexane ethyl acetate to give the title compound (92%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06329550B1 |
| Source dataset | uspto-grants-2001_12 |
| ORD ID | ord-f9b9039da2a0488c81ffdcd764e7fffd |
| Source note | uspto-grants-2001_12 |