HCID 53943686, compound → HCID 57272130, compound

HRID 2269832Notes

Reaction equation

HRID 2269832 reaction equation
FC(F)(F)C(O)=O.[CH2:8]([NH:16][C:17](=[O:31])[CH:18]([NH2:30])[C:19]([NH:21][CH2:22][CH2:23][C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1)=[O:20])[CH2:9][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1.[Br:32][C@H:33]([CH2:37][CH2:38][CH2:39][CH2:40][N:41]1[C:45](=[O:46])[C:44]2=[CH:47][CH:48]=[CH:49][CH:50]=[C:43]2[C:42]1=[O:51])[C:34](O)=[O:35]>>[CH2:22]([NH:21][C:19](=[O:20])[CH:18]([NH:30][C:34](=[O:35])[C@@H:33]([Br:32])[CH2:37][CH2:38][CH2:39][CH2:40][N:41]1[C:45](=[O:46])[C:44]2=[CH:47][CH:48]=[CH:49][CH:50]=[C:43]2[C:42]1=[O:51])[C:17]([NH:16][CH2:8][CH2:9][C:10]1[CH:11]=[CH:12][CH:13]=[CH:14][CH:15]=1)=[O:31])[CH2:23][C:24]1[CH:25]=[CH:26][CH:27]=[CH:28][CH:29]=1

Participants

3

Reactant 2

HCID 53943686HCID 53943686, compoundHCID 69989911HCID 69989911, compound

Product 1

HCID 57272130HCID 57272130, compound

Procedure

Prepare by the method of Example 3.3 using N,N′-diphenethyl-2-aminomalonamide trifluoroacetic acid salt (20 mmol) and (R)-2-bromo-6-phthalimidohexanoic acid (25 mmol) to give the title compound.

Sources & evidence

ORD record
ord-1b37be2c2005494f94335e8a6f43475d
Source dataset
uspto-grants-2001_12
Patent number
US06329550B1

Reaction notes

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