HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(3,4,5-Trimethoxy-benzoyl)-3-phenyl-3-(2-methanesulfonyl-ethyl)-pyrrolidine → (3-{2-[4-(1-Furan-2-ylmethyl-1H-benzoimidazole-2-carbonyl)-piperidin-1-yl]-ethyl}-3-phenyl-pyrrolidin-1-yl)-(3,4,5-trimethoxy-phenyl)-methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(3,4,5-Trimethoxy-benzoyl)-3-phenyl-3-(2-methanesulfonyl-ethyl)-pyrrolidine | HCID 15542888 | — |
| Reactant | 4-(1-(fur-2-ylmethyl)-1H-benzimidazole-2-carbonyl)piperidine | HCID 18333519 | — |
| Solvent | Acetone hexane | HCID 21880519 | — |
| Product | (3-{2-[4-(1-Furan-2-ylmethyl-1H-benzoimidazole-2-carbonyl)-piperidin-1-yl]-ethyl}-3-phenyl-pyrrolidin-1-yl)-(3,4,5-trimethoxy-phenyl)-methanone | HCID 10168749 | — |
Reaction Steps
Prepare by the method of Example 6.6.2 using 1-(3,4,5-trimethoxy-benzoyl)-3-phenyl-3-(2-methanesulfonyl-ethyl)-pyrrolidine and 4-(1-(fur-2-ylmethyl)-1 H-benzoimidazole-2-carbonyl)-piperidine obtain, after chromatography on silica gel eluting with 80% acetone/hexane, the title compound: Mass Spectra (CI/NH3) M++H=677.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06329392B1 |
| Source dataset | uspto-grants-2001_12 |
| ORD ID | ord-8255c410793448bc96599c7696fd4c0e |
| Source note | uspto-grants-2001_12 |