HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(Trifluoromethyl)benzyl chloride → 1-(3,4,5-Trimethoxy-benzoyl)-3-[2-[4-[1-(3-trifluoromethyl-benzyl)-1 H-benzoimidazole-2-carbonyl]-piperidin-1-yl]-ethyl]-3-phenyl-pyrrolidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(Trifluoromethyl)benzyl chloride | HCID 69716 | — |
| Reactant | 1-(3,4,5-trimethoxy-benzoyl)-3-[2-[4-[1H-benzoimidazole-2-carbonyl]-piperidin-1-yl]-ethyl]-3-phenyl-pyrrolidine | HCID 10121390 | — |
| Product | 1-(3,4,5-Trimethoxy-benzoyl)-3-[2-[4-[1-(3-trifluoromethyl-benzyl)-1 H-benzoimidazole-2-carbonyl]-piperidin-1-yl]-ethyl]-3-phenyl-pyrrolidine | HCID 15542870 | — |
Reaction Steps
Prepare by the method of Example 38.1 using 1-(3,4,5-trimethoxy-benzoyl)-3-[2-[4-[1H-benzoimidazole-2-carbonyl]-piperidin-1-yl]-ethyl]-3-phenyl-pyrrolidine and 3-trifluormethylbenzyl chloride to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06329392B1 |
| Source dataset | uspto-grants-2001_12 |
| ORD ID | ord-6abfbc7af47b480fae565a994c9d9c3f |
| Source note | uspto-grants-2001_12 |