HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(1-(4-fluorobenzyl)-1H-benzoimidazol-2-yl)-4-hydroxypiperidine → HCID 10123008, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(1-(4-fluorobenzyl)-1H-benzoimidazol-2-yl)-4-hydroxypiperidine | HCID 15542885 | — |
| Reactant | HCID 18333324 | HCID 18333324 | — |
| Product | HCID 10123008 | HCID 10123008 | — |
Reaction Steps
Prepare by the method of Example 6.6.2 using 1-(3,4,5-trimethoxy-benzyl)-3-(4-fluoro-phenylmethyl)-3-(2-methanesulfonyl-ethyl)-2-oxo-pyrrolidine and 4-[l-(4-fluoro-benzyl)-1H-benzoimidazol-2-yl]-4-hydroxy-piperidine to give the title compound: Rf=0.38 (silica gel, 30% methanol/ethyl acetate).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06329392B1 |
| Source dataset | uspto-grants-2001_12 |
| ORD ID | ord-e1f4fccfdd684bcaab3ffd511a52629d |
| Source note | uspto-grants-2001_12 |