HCID 15228076, compound → HCID 18333265, compound

HRID 2269890Notes

Reaction equation

[CH2:1]([C:3]1[C:27]([O:28][CH3:29])=[CH:26][C:6]([C:7]([N:9]2[CH2:13][CH2:12][C:11]([C:20]3[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=3)([CH2:14][CH2:15]S(C)(=O)=O)[CH2:10]2)=[O:8])=[C:5]([O:30][C:31](=[O:33])[CH3:32])[C:4]=1[O:34][CH3:35])[CH3:2].[CH2:36]([O:38][CH2:39][CH2:40][N:41]1[C:45]2[CH:46]=[CH:47][CH:48]=[CH:49][C:44]=2[N:43]=[C:42]1[C:50]([CH:52]1[CH2:57][CH2:56][NH:55][CH2:54][CH2:53]1)=[O:51])[CH3:37]>>[CH2:1]([C:3]1[C:27]([O:28][CH3:29])=[CH:26][C:6]([C:7]([N:9]2[CH2:13][CH2:12][C:11]([CH2:14][CH2:15][N:55]3[CH2:56][CH2:57][CH:52]([C:50]([C:42]4[N:41]([CH2:40][CH2:39][O:38][CH2:36][CH3:37])[C:45]5[CH:46]=[CH:47][CH:48]=[CH:49][C:44]=5[N:43]=4)=[O:51])[CH2:53][CH2:54]3)([C:20]3[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=3)[CH2:10]2)=[O:8])=[C:5]([O:30][C:31](=[O:33])[CH3:32])[C:4]=1[O:34][CH3:35])[CH3:2]

Participants

Reactant 2

HCID 15228076HCID 15228076, compound

HCID 18333478HCID 18333478, compound

Product 1

HCID 18333265HCID 18333265, compound

Procedure

Prepare by the method of Example 6.6.2 using 1-(4-ethyl acetoxy-3,5-dimethoxy-benzoyl)-3-phenyl-3-(2-methanesulfonyl-ethyl)-pyrrolidine and 4-[1-(2-ethoxy-ethyl)-1H-benzoimidazole-2-carbonyl]-piperidine to give the title compound.

Sources & evidence

ORD record: ord-e26e3a3399b445fab6fe498f7101a7df
Source dataset: uspto-grants-2001_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06329392B1

Reaction notes

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