HuagongsheHuagongshe Chemistry Print Report · For research reference only
Aniline → 3-(4-Methoxy-3-methyl-benzoyl)-1H-quinolin-4-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Aniline | HCID 6115 | — |
| Reactant | 3-Ethoxy-2-(4-methoxy-3-methyl-benzoyl)-acrylic acid methyl ester | HCID 66878626 | — |
| Solvent | Diphenyl Ether | HCID 7583 | — |
| Product | 3-(4-Methoxy-3-methyl-benzoyl)-1H-quinolin-4-one | HCID 57754758 | 101% |
Reaction Steps
Experimental conditions analogous to those described for Step 1 of Example 1 were used with 1 g (3.78 mmol) of 3-ethoxy-2-(4-methoxy-3-methyl-benzoyl)-acrylic acid methyl ester, 0.214 g (3.78 mmol) of aniline, and 20 mL of diphenyl ether to yield 1.12 g of 3-(4-Methoxy-3-methyl-benzoyl)-1H-quinolin-4-one.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07557213B2 |
| Source dataset | uspto-grants-2009_07 |
| ORD ID | ord-cd23c874ceec475c8f9c1e82dc654fdd |
| Source note | uspto-grants-2009_07 |