Sodium Azide → HCID 54553818, compound

Participants

Reaction Conditions

Reaction Steps

To a 8 ml DMF solution of 580 mg (2.61 mmol) of (1R,3S)-3-[(methylsulfonyl)oxy]cyclopentyl acetate, 203 mg (3.13 mmol) of sodium azide and 26 μl (0.13 mmol) of 15-crown-5-ether were added and stirred at 80° C. for 3 hours, followed by concentrating and then by diluting with 50 ml of diethyl ether. The residue was washed with 10 ml of saturated saline and then the solvent was distilled off to obtain 360 mg (82%) of the above-identified compound as a slightly brown oily substance.

Provenance & Evidence