HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diisopropylamine → HCID 22632872, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diisopropylamine | HCID 7912 | — |
| Reactant | 3-Fluoroaniline | HCID 9742 | — |
| Reactant | 2,4,5-Trifluorobenzoic acid | HCID 521170 | — |
| Reactant | Butyllithium | HCID 178418339 | — |
| Product | HCID 22632872 | HCID 22632872 | 93.3% |
Reaction Steps
Using General Method 1, the reaction of 2.5 M solution of n-BuLi in hexanes (21 mL, 53 mmol), diisopropylamine (7.2 mL, 51 mmol), 3-fluoro-aniline (1.6 mL, 17 mmol), and 2,4,5-trifluorobenzoic acid (3.0 g, 17 mmol) provided 4.24 g of the crude title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06331538B1 |
| Source dataset | uspto-grants-2001_12 |
| ORD ID | ord-9ff12057e004408b8582c7b4b61ac8f6 |
| Source note | uspto-grants-2001_12 |